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The Northwestern University Feinberg School of Medicine Division of Reproductive Endocrinology and Infertility has an extensive research enterprise. Each of our faculty members is involved in multiple research studies. In addition to lab studies, numerous clinical studies relate to various aspects of reproduction and infertility. In particular, we conduct studies associated with fertility preservation.
ACTorNOT Trial (Persisting PULs)
Evaluates three management strategies (MTX vs. D&C vs. Expectant Observation) in pregnant women who have persisting PULs to determine the most effective at resolving a PPUL without requiring any additional treatment afterwards.
Natera Multiple Gestation
Aims to develop a method of minimally invasive prenatal diagnosis for multiple gestation pregnancies (twins) that has a higher sensitivity and lower false positive rate than current available screening tests.
EPPC – Prospective Cohort Assessing Novel Biomarkers of Early Pregnancy
Aims to identify novel human serum, plasma protein and tissue biomarkers that distinguish normal pregnancy from abnormal pregnancy.
Liberty 2 Myovant Uterine Fibroid
To determine the benefit of relugolix 40 mg once daily, co-administered with low-dose estradiol and norethindrone acetate, compared with placebo for 24 weeks to address heavy menstrual bleeding associated with uterine fibroids in women ages 18 to 50.
Breaking Down Financial Barriers: A Pilot Study to Determine the Feasibility, Acceptance, and Effectiveness of In Vitro Maturation in Low Resource Populations
A feasibility and acceptability study of in vitro maturation (IVM) in low-income couples, in which we will determine the feasibility, acceptance and cost benefit of IVM as compared to in vitro fertilization (IVF) in low-income populations.
Prevalence of Aneuploidy in Ectopic Pregnancies
The purpose of this study is to evaluate genetic associations with ectopic pregnancies. It has commonly been thought that ectopic pregnancies are caused from fallopian tube damage or other maternal factors. However, a newer theory has emerged that ectopic pregnancies may implant outside of the uterus because they are chromosomally abnormal.
The tissue from the ectopic pregnancy, removed at the time of surgery, will undergo genetic testing to identify if the pregnancy implanted in the wrong place due to a genetic abnormality with the fetus.
Learn more about our research activities via the Feinberg School of Medicine Obstetrics and Gynecology research section.
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